Week 16 · 16 games · December 21, 2025 · Updated Jul 9, 12:06 AM ET
The Almanac's Take
Cleveland is the story this week. BUF-CLE sits at 41.5 with 25-degree temps and 16 mph winds off Lake Erie — that's a punishing combination for a total that's already modest. MetLife isn't far behind: MIN-NYG carries a 41.5 total too, and 20 mph wind at an open stadium in late December will test every deep route on the field. Seattle and LA square off at 42.5 with 17 mph gusts, so three of the slate's windiest games are also among its lower totals — the market is already pricing the elements in. The indoor games, including PIT-DET at 52.5 and LAC-DAL at 50.5, are where the points projections breathe freely.
Los Angeles Rams at Seattle Seahawks
Thu 8:15 PM ET
Lumen Field
Conditions
OutdoorField Turf51°F17 mph wind
Vegas line
SEA -1.5O/U 42.5
Philadelphia Eagles at Washington Commanders
Sat 5:00 PM ET
FedExField
Conditions
OutdoorGrass42°F7 mph wind
Vegas line
PHI -7O/U 43.5
Green Bay Packers at Chicago Bears
Sat 8:20 PM ET
Soldier Field
Conditions
OutdoorGrass37°F6 mph wind
Vegas line
CHI -1.5O/U 45.5
Buffalo Bills at Cleveland Browns
Sun 1:00 PM ET
FirstEnergy Stadium
Conditions
OutdoorGrass25°F16 mph wind
Vegas line
BUF -10.5O/U 41.5
Cincinnati Bengals at Miami Dolphins
Sun 1:00 PM ET
Hard Rock Stadium
Conditions
OutdoorGrass81°F7 mph wind
Vegas line
CIN -3.5O/U 48.5
Kansas City Chiefs at Tennessee Titans
Sun 1:00 PM ET
Nissan Stadium
Conditions
OutdoorGrass51°F8 mph wind
Vegas line
KC -3.5O/U 37.5
Los Angeles Chargers at Dallas Cowboys
Sun 1:00 PM ET
AT&T Stadium
Conditions
IndoorsMatrixTurf
Vegas line
DAL -1.5O/U 50.5
Minnesota Vikings at New York Giants
Sun 1:00 PM ET
MetLife Stadium
Conditions
OutdoorField Turf46°F20 mph wind
Vegas line
MIN -2.5O/U 41.5
New York Jets at New Orleans Saints
Sun 1:00 PM ET
Mercedes-Benz Superdome
Conditions
IndoorsSportTurf
Vegas line
NO -6.5O/U 39.5
Tampa Bay Buccaneers at Carolina Panthers
Sun 1:00 PM ET
Bank of America Stadium
Conditions
OutdoorGrass61°F8 mph wind
Vegas line
TB -3O/U 44.5
Atlanta Falcons at Arizona Cardinals
Sun 4:05 PM ET
State Farm Stadium
Conditions
IndoorsGrass
Vegas line
ATL -2.5O/U 48.5
Jacksonville Jaguars at Denver Broncos
Sun 4:05 PM ET
Empower Field at Mile High
Conditions
OutdoorGrass62°F3 mph wind
Vegas line
DEN -3.5O/U 46.5
Las Vegas Raiders at Houston Texans
Sun 4:25 PM ET
NRG Stadium
Conditions
IndoorsAstroTurf
Vegas line
HOU -14.5O/U 39.5
Pittsburgh Steelers at Detroit Lions
Sun 4:25 PM ET
Ford Field
Conditions
IndoorsField Turf
Vegas line
DET -7.5O/U 52.5
New England Patriots at Baltimore Ravens
Sun 8:20 PM ET
M&T Bank Stadium
Conditions
OutdoorGrass40°F2 mph wind
Vegas line
BAL -3.5O/U 48.5
San Francisco 49ers at Indianapolis Colts
Mon 8:15 PM ET
Lucas Oil Stadium
Conditions
IndoorsField Turf
Vegas line
SF -4.5O/U 46.5
Methodology
Conditions and venue come from the nflverse schedules feed. Temperature and wind are shown only when forecast — they are blank (never zero) for dome/closed-roof games and for outdoor games whose forecast hasn't posted yet. The spread is shown in favorite form; a positive home line in the source feed means the home team is favored. Lines are the market's, for context — not a betting recommendation.
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