Week 4 · 16 games · September 28, 2025 · Updated Jul 9, 12:04 AM ET
The Almanac's Take
Miami is the wind story of the week — Jets-Dolphins carries 17 mph at Hard Rock with a 44.5 total, the kind of number that already prices in some offensive friction. Kansas City and Baltimore share the same 48.5 total under 10 mph winds at 89 degrees, warm enough that it's not a factor. Denver hosts Cincinnati at 66 degrees with 12 mph gusts and a 44.5 total, the quieter wind game worth watching. Half the slate — Arizona, Detroit, Houston, Atlanta, LA, Las Vegas, Dallas — is indoors, conditions irrelevant. Everything else is mild and effectively weather-neutral.
Seattle Seahawks at Arizona Cardinals
Thu 8:15 PM ET
State Farm Stadium
Conditions
IndoorsGrass
Vegas line
SEA -1.5O/U 43.5
Minnesota Vikings at Pittsburgh Steelers
Sun 9:30 AM ET
Acrisure Stadium · Neutral site
Conditions
OutdoorGrass61°F5 mph wind
Vegas line
MIN -2.5O/U 41.5
Carolina Panthers at New England Patriots
Sun 1:00 PM ET
Gillette Stadium
Conditions
OutdoorField Turf76°F7 mph wind
Vegas line
NE -5.5O/U 42.5
Cleveland Browns at Detroit Lions
Sun 1:00 PM ET
Ford Field
Conditions
IndoorsField Turf
Vegas line
DET -10O/U 44.5
Los Angeles Chargers at New York Giants
Sun 1:00 PM ET
MetLife Stadium
Conditions
OutdoorField Turf81°F4 mph wind
Vegas line
LAC -6O/U 43.5
New Orleans Saints at Buffalo Bills
Sun 1:00 PM ET
New Era Field
Conditions
OutdoorA-Turf73°F7 mph wind
Vegas line
BUF -15.5O/U 48.5
Philadelphia Eagles at Tampa Bay Buccaneers
Sun 1:00 PM ET
Raymond James Stadium
Conditions
OutdoorGrass88°F6 mph wind
Vegas line
PHI -3.5O/U 44.5
Tennessee Titans at Houston Texans
Sun 1:00 PM ET
NRG Stadium
Conditions
IndoorsAstroTurf
Vegas line
HOU -7.5O/U 39.5
Washington Commanders at Atlanta Falcons
Sun 1:00 PM ET
Mercedes-Benz Stadium
Conditions
IndoorsField Turf
Vegas line
ATL -2.5O/U 43.5
Indianapolis Colts at Los Angeles Rams
Sun 4:05 PM ET
SoFi Stadium
Conditions
IndoorsMatrixTurf
Vegas line
LA -3.5O/U 49.5
Jacksonville Jaguars at San Francisco 49ers
Sun 4:05 PM ET
Levi's Stadium
Conditions
OutdoorGrass72°F7 mph wind
Vegas line
SF -3.5O/U 45.5
Baltimore Ravens at Kansas City Chiefs
Sun 4:25 PM ET
GEHA Field at Arrowhead Stadium
Conditions
OutdoorGrass89°F10 mph wind
Vegas line
BAL -2.5O/U 48.5
Chicago Bears at Las Vegas Raiders
Sun 4:25 PM ET
Allegiant Stadium
Conditions
IndoorsGrass
Vegas line
LV -1.5O/U 47.5
Green Bay Packers at Dallas Cowboys
Sun 8:20 PM ET
AT&T Stadium
Conditions
IndoorsMatrixTurf
Vegas line
GB -7O/U 47.5
New York Jets at Miami Dolphins
Mon 7:15 PM ET
Hard Rock Stadium
Conditions
OutdoorGrass88°F17 mph wind
Vegas line
MIA -2.5O/U 44.5
Cincinnati Bengals at Denver Broncos
Mon 8:15 PM ET
Empower Field at Mile High
Conditions
OutdoorGrass66°F12 mph wind
Vegas line
DEN -7.5O/U 44.5
Methodology
Conditions and venue come from the nflverse schedules feed. Temperature and wind are shown only when forecast — they are blank (never zero) for dome/closed-roof games and for outdoor games whose forecast hasn't posted yet. The spread is shown in favorite form; a positive home line in the source feed means the home team is favored. Lines are the market's, for context — not a betting recommendation.
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